Analytical Testing Services
Selection Guide for Oxidative Stress Biomarker Testing
Class |
Biomarker |
Sample |
Remarks |
|
DNA Damage |
Urine 8-OHdG |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
|
Serum/Plasma 8-OHdG |
750 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
||
Lipid Damage |
Urine 8-epi-PGF2a |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
|
Urine Total
Alkenals |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
||
Serum/Plasma Total
Alkenals (MDA + 4-HNE) |
750 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
||
Urine Hexanoyl-Lysine |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
||
750 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
|||
Protein Damage |
Urine
Nitrotyrosine |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
|
Serum/Plasma Nitrotyrosine (DT) (Cat. No: BLNT) |
750 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
||
Normalizing Factor |
Urine Creatinine (Cat. No: URCREA) |
500 uL frozen Urine |
Preferred sample is an aliquot from 24hr pooled collection. Next best is an aliquot from first morning voided urine. |
|
Antioxidant
Factors |
Serum/Plasma
WHOLE ORAC |
500 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
|
Tissue
Homogenate WHOLE ORAC |
500 uL frozen Tissue Homogenate |
Centrifuge the homogenate and freeze the clear supernatant. |
||
Plant/NaturalProducts/Food/Pet
Food/Dietary Supplements WHOLE ORAC |
10 ml of Liquid Sample; 5g of powder sample; 10g of tablet/caplet/capsule |
Powder/solid sample will be extracted in appropriate solvent prior to testing. |
||
Antioxidant
Factors |
Serum
Lipid Soluble Antioxidants – Carotenoid Panel -
Lutein, Zeaxanthine, a-carotene, b-carotene, b-cryptoxanthine,
lycopene, retinol, and retinyl palmitate |
600 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
|
Tissue
Homogenate Lipid Soluble Antioxidants – Carotenoid
Panel - Lutein, Zeaxanthine, a-carotene, b-carotene, b-cryptoxanthine,
lycopene, retinol, and retinyl palmitate |
600 uL frozen Tissue Homogenate |
Centrifuge the homogenate and freeze the clear supernatant. |
||
Plant/NaturalProducts/Food/Pet
Food/Dietary Supplements – Carotenoid Panel -
Lutein, Zeaxanthine, a-carotene, b-carotene, b-cryptoxanthine,
lycopene, retinol, and retinyl palmitate |
10 ml of Liquid Sample; 5g of powder sample; 10g of tablet/caplet/capsule |
Powder/solid samples will be extracted in appropriate solvent prior to testing. |
||
Antioxidant
Factors |
Serum
Lipid Soluble Antioxidants – Vitamin E Panel -
a-tocopherol, d-tocopherol, and g-tocopherol |
600 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
|
Tissue
Homogenate Lipid Soluble Antioxidants – Vitamin
E Panel - a-tocopherol, d-tocopherol, and g-tocopherol |
600 uL frozen Tissue Homogenate |
Centrifuge the homogenate and freeze the clear supernatant. |
||
Plant
/ Natural Products / Food / Pet Food / Dietary Supplements – Vitamin
E Panel - a-tocopherol, d-tocopherol, and g-tocopherol |
10 ml of Liquid Sample; 5g of powder sample; 10g of tablet/caplet/capsule |
Powder/solid samples will be extracted in appropriate solvent prior to testing. |
||
Antioxidant
Factors |
Serum
Lipid Soluble Antioxidants – Coenzyme Q10 |
600 uL frozen Serum/Plasma |
Lipemic and hemolysed samples are unacceptable. Blood should be drawn after an overnight fasting for about 8hr. |
|
Tissue
Homogenate Lipid Soluble Antioxidants – Coenzyme
Q10 |
600 uL frozen Tissue Homogenate |
Centrifuge the homogenate and freeze the clear supernatant. |
||
Plant
/ Natural Products / Food / Pet Food / Dietary Supplements – Coenzyme
Q10 |
10 ml of Liquid Sample; 5g of powder sample; 10g of tablet/caplet/capsule |
Powder/solid samples will be extracted in appropriate solvent prior to testing. |
||
Note:
Genox’s Products are for RESEARCH USE ONLY. The provision of test reports, generated
by using Genox's products, to individuals © Copyright 1996-2008 Genox Corporation. All rights reserved |
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