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Biomarkers for lipid oxidation. oxidative stress
Anti Crotonaldehyde monoclonal antibody. Anti Crotonaldehyde monoclonal antibody. Anti Crotonaldehyde monoclonal antibody.
Suitable for immunohistocheistry. For research use only.
About crotonaldehyde (CRA)
Crotonaldehyde (CRA) is a representative carcinogenic aldehyde formed endogenously through lipid peroxidation. CRA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with CRA and lysine residue leads to the formation of numerous numbers of adducts. This antibody is specific for the CRA-modified protein.
Subclass: Mouse IgG2b (lambda), clone 82D3
Antigen: CRA-modified keyhole-lympet hemocyanine
Specificity: Specific for CRA-modified protein (especially CRA-lysine adduct)
Form: Frozen (100 µg/mL antibody in 10mM PBS containing 0.1% NaN3 and 0.5% BSA). Purified by Protein-A.
Storage: Less than -20°C
Application: Immunohistochemistry.
Recommended antibody concentration is 0.5-1.0 µg/mL on paraformaldehyde fixed tissue.
1) Endogenous formation of protein adducts with carcinogenic aldehydes.
K Ichihashi, T Osawa, S Toyokuni, K Uchida J Biol Chem 276(26), p23903-23913 (2001)
Product name Code Content
Anti Crotonaldehyde (CRA) monoclonal antibody MCA-030n 30 µg IgG

Manufactured by NOF corporation, Japan.

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